Vitamin D in inflammatory diseases

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Vitamin D in inflammatory diseases

Changes in vitamin D serum levels have been associated with inflammatory diseases, such as inflammatory bowel disease (IBD), rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis (MS), atherosclerosis, or asthma. Genome- and transcriptome-wide studies indicate that vitamin D signaling modulates many inflammatory responses on several levels. This includes (i) the regulation of t...

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Vitamin D and inflammatory diseases

Beyond its critical function in calcium homeostasis, vitamin D has recently been found to play an important role in the modulation of the immune/inflammation system via regulating the production of inflammatory cytokines and inhibiting the proliferation of proinflammatory cells, both of which are crucial for the pathogenesis of inflammatory diseases. Several studies have associated lower vitami...

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Impact of Low Vitamin D Level on Inflammatory Bowel Diseases

Submit Manuscript | http://medcraveonline.com Anti-carcinogenic activity of vitamin D comprises promotion of cell differentiation, induction of apoptosis, inhibition of cancer cell proliferation, regulation of expression of different proinflammatory cytokines and growth factors, as well anti angiogenic properties [2,3]. However, the evidence that vitamin D prevents development of colon cancer i...

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Review article: vitamin D and inflammatory bowel diseases.

BACKGROUND Vitamin D is traditionally associated with bone metabolism. The immunological effects of vitamin D have increasingly come into focus. AIM To review the evidence supporting a role of vitamin D in inflammatory bowel diseases. METHODS A comprehensive search was performed on PubMed using the terms 'crohn's disease' 'ulcerative colitis' and 'vitamin D'. RESULTS Vitamin D deficiency ...

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Vitamin D-resistant diseases.

Hereditary vitamin D receptor defects (HVDRDs) is a more appropriate and precise title for an inborn error of metabolism commonly known as pseudo-vitamin D deficiency or vitamin D dependency, type II. It is a rare autosomal recessive disorder, approximately 70 kindreds were described, but its main importance is elucidating the physiology of vitamin D and calcium homeostasis in humans. Patients ...

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ژورنال

عنوان ژورنال: Frontiers in Physiology

سال: 2014

ISSN: 1664-042X

DOI: 10.3389/fphys.2014.00244